Alzheimer's disease (AD) is the most common neurodegenerative disease. β - amyloid protein can oligomerize, aggregate and then form the neurotoxic fragments of plaque. Clinical manifestations include the presence of intracellular nerve fiber tangles and extracellular amyloid plaques, which can lead to neuronal dysfunction and cell death.
β - amyloid protein is considered to be the central molecule of Alzheimer's disease. The research on the fragment of amyloid β - protein (12-28) can help us to understand the whole β - amyloid protein and provide a theoretical support for the elimination of β - amyloid in vivo.
At the same time, amyloid β - protein (12-28) has better solubility, which provides a great help for the researchIn the solubility test, there are professional technicians in the QC department of GoTop Peptide Biotceh to test the solubility of each peptide produced. It is proved that the water solubility of Amyloid β-Protein (12-28) is very good. In addition to the water solubility experiment, Go Top Peptide Biotceh can also complete a variety of solubility experiments required by customers.